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Enhanced interaction of L-selectin with the high endothelial venule ligand via selectively oxidized sialic acids.

The selectins are adhesion receptors that play key roles in leukocyte trafficking. Each has an N-terminal C-type lectin domain that binds to specific carbohydrates in a calcium-dependent manner. L-selectin recognizes sulfated, sialylated ligands on lymph node high endothelial venules. This recogniti...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Norgard, K E, Han, H, Powell, L, Kriegler, M, Varki, A, Varki, N M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.3.1068
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