High Frequency of Haplotype HLA-DQ7 in Celiac Disease Patients from South Italy: Retrospective Evaluation of 5,535 Subjects at Risk of Celiac Disease

BACKGROUND: Celiac disease (CD) has a strong genetic component mainly due to HLA DQ2/DQ8 encoding genes. However, a minority of CD patients are DQ2/DQ8-negative. To address this issue, we retrospectively characterized HLA haplotypes in 5,535 subjects at risk of CD (either relatives of CD patients or...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tinto, Nadia, Cola, Arturo, Piscopo, Chiara, Capuano, Marina, Galatola, Martina, Greco, Luigi, Sacchetti, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580462/
https://ncbi.nlm.nih.gov/pubmed/26398634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138324
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