Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

BACKGROUND: Carcinoma of the oral tongue (OTSCC) is the most common malignancy of the oral cavity, characterized by frequent recurrence and poor survival. The last three decades has witnessed a change in the OTSCC epidemiological profile, with increasing incidence in younger patients, females and ne...

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Publicado en:Genome Med
Autores principales: Vettore, Andre Luiz, Ramnarayanan, Kalpana, Poore, Gregory, Lim, Kevin, Ong, Choon Kiat, Huang, Kie Kyon, Leong, Hui Sun, Chong, Fui Teen, Lim, Tony Kiat-Hon, Lim, Weng Khong, Cutcutache, Ioana, Mcpherson, John R., Suzuki, Yuka, Zhang, Shenli, Skanthakumar, Thakshayeni, Wang, Weining, Tan, Daniel SW, Cho, Byoung Chul, Teh, Bin Tean, Rozen, Steve, Tan, Patrick, Iyer, N. Gopalakrishna
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580363/
https://ncbi.nlm.nih.gov/pubmed/26395002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0219-2
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