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PI3K pathway inhibitors: potential prospects as adjuncts to vaccine immunotherapy for glioblastoma
Constitutive activation of the PI3K pathway has been implicated in glioblastoma (GBM) pathogenesis. Pharmacologic inhibition can both inhibit tumor survival and downregulate expression of programmed death ligand-1, a protein highly expressed on glioma cells that strongly contributes to cancer immuno...
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| Udgivet i: | Immunotherapy |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580256/ https://ncbi.nlm.nih.gov/pubmed/25186604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.35 |
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