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Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis

BACKGROUND: Nucleoside Diphosphate Kinase (NDPK), described as NM23 a metastasis suppressor, is found in the culture medium of cancer cells lines suggesting that the kinase may have an extracellular role. We propose that extracellular NM23 released from breast cancers in vivo stimulates tumor cell m...

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Pubblicato in:Integr Cancer Sci Ther
Autori principali: Yokdang, Nucharee, Nordmeier, Senny, Speirs, Katie, Burkin, Heather R., Buxton, Iain L. O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580248/
https://ncbi.nlm.nih.gov/pubmed/26413311
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