Pigment epithelium-derived factor inhibits caveolin-induced interleukin-8 gene expression and proliferation of human prostate cancer cells

Caveolin-1 (Cav), a primary protein component of caveolae, is overexpressed in prostate cancer, thereby promoting growth and metastasis of this tumor. By contrast, pigment epithelium-derived factor (PEDF) has been shown to inhibit tumor growth and metastasis, including that of prostate cancer, via i...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: MATSUI, TAKANORI, OJIMA, AYAKO, HIGASHIMOTO, YUICHIRO, TAIRA, JUNICHI, FUKAMI, KEI, YAMAGISHI, SHO-ICHI
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580074/
https://ncbi.nlm.nih.gov/pubmed/26622904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3568
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