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Prevalence of KRAS, BRAF, PI3K and EGFR mutations among Asian patients with metastatic colorectal cancer

Mutations in oncogenes along the epidermal growth factor receptor (EGFR) signaling pathway have been implicated in the resistance to cetuximab in patients with metastatic colorectal cancer (mCRC). However, the relative significance of these mutations based on their frequencies of occurrence in the S...

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Publicat a:Oncol Lett
Autors principals: PHUA, LEE CHENG, NG, HUI WEN, YEO, ANGIE HUI LING, CHEN, ELYA, LO, MICHELLE SHU MEI, CHEAH, PEH YEAN, CHAN, ERIC CHUN YONG, KOH, POH KOON, HO, HAN KIAT
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579971/
https://ncbi.nlm.nih.gov/pubmed/26622882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3560
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