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Measurement of apoptotic and necrotic cell death in primary hepatocyte cultures

Hepatotoxicity, including drug-induced liver injury, is frequently accompanied by cell death. The latter is typically driven by apoptosis or necrosis, which substantially differ based upon biochemical and morphological criteria. The present chapter describes 2 commonly used methods to probe apoptoti...

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Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Maes, Michaël, Vanhaecke, Tamara, Cogliati, Bruno, Crespo Yanguas, Sara, Willebrords, Joost, Rogiers, Vera, Vinken, Mathieu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579552/
https://ncbi.nlm.nih.gov/pubmed/26272157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2074-7_27
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