REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans

The Caenorhabditis elegans gene rec-1 was the first genetic locus identified in metazoa to affect the distribution of meiotic crossovers along the chromosome. We report that rec-1 encodes a distant paralog of HIM-5, which was discovered by whole-genome sequencing and confirmed by multiple genome-edi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Chung, George, Rose, Ann M., Petalcorin, Mark I.R., Martin, Julie S., Kessler, Zebulin, Sanchez-Pulido, Luis, Ponting, Chris P., Yanowitz, Judith L., Boulton, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579353/
https://ncbi.nlm.nih.gov/pubmed/26385965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.266056.115
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