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Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes

The small GTPase RAB-5/Rab5 is a master regulator of the early endosome, required for a myriad of coordinated activities, including the degradation and recycling of internalized cargo. Here we focused on the recycling function of the early endosome and the regulation of RAB-5 by GAP protein TBC-2 in...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Liu, Ou, Grant, Barth D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578947/
https://ncbi.nlm.nih.gov/pubmed/26393361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005514
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