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c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing’s Sarcoma Cell Line

Myc oncogenic transcription factor is known to inhibit tumor suppressive microRNAs (miRNAs), resulting in greater expression of their target protein related to cell cycle, invasion or anti-apoptotic factors in human cancer cells. To explore possible oncogenic factors in Ewing’s sarcoma (ES), we cond...

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發表在:PLoS One
Main Authors: Kawano, Masanori, Tanaka, Kazuhiro, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578885/
https://ncbi.nlm.nih.gov/pubmed/26393798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138560
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