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c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing’s Sarcoma Cell Line

Myc oncogenic transcription factor is known to inhibit tumor suppressive microRNAs (miRNAs), resulting in greater expression of their target protein related to cell cycle, invasion or anti-apoptotic factors in human cancer cells. To explore possible oncogenic factors in Ewing’s sarcoma (ES), we cond...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kawano, Masanori, Tanaka, Kazuhiro, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578885/
https://ncbi.nlm.nih.gov/pubmed/26393798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138560
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