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Dexamethasone-Induced Insulin Resistance: Kinetic Modeling Using Novel PET Radiopharmaceutical 6-Deoxy-6-[(18)F]fluoro-D-glucose

PURPOSE: An insulin-resistant rat model, induced by dexamethasone, was used to evaluate a Michaelis–Menten-based kinetic model using 6-deoxy-6-[(18)F]fluoro-D-glucose (6-[(18)F]FDG) to quantify glucose transport with PET. PROCEDURES: Seventeen, male, Sprague–Dawley rats were studied in three groups:...

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Vydáno v:Mol Imaging Biol
Hlavní autoři: Su, Kuan-Hao, Chandramouli, Visvanathan, Ismail-Beigi, Faramarz, Muzic, Raymond F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578717/
https://ncbi.nlm.nih.gov/pubmed/24819311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0737-0
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