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Neonatal microbial colonization in mice promotes prolonged dominance of CD11b(+)Gr-1(+) cells and accelerated establishment of the CD4(+) T cell population in the spleen

To assess the microbial influence on postnatal hematopoiesis, we examined the role of early life microbial colonization on the composition of leukocyte subsets in the neonatal spleen. A high number of CD11b(+)Gr-1(+) splenocytes present perinatally was sustained for a longer period in conventionally...

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Publicat a:Immun Inflamm Dis
Autors principals: Kristensen, Matilde B, Metzdorff, Stine B, Bergström, Anders, Damlund, Dina S M, Fink, Lisbeth N, Licht, Tine R, Frøkiær, Hanne
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578529/
https://ncbi.nlm.nih.gov/pubmed/26417445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.70
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