IL-27 and TGFβ mediated expansion of Th1 and adaptive regulatory T cells expressing IL-10 correlates with bacterial burden and disease severity in pulmonary tuberculosis

CD4(+) T cell expression of IL-10 is an important mechanism controlling immunity to tuberculosis (TB). To identify the CD4(+) T cell subsets producing IL-10 in human TB, we enumerated the frequencies of IL-10 expressing CD4(+) T cell subsets following TB—antigen stimulation of cells from individuals...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Kumar, Nathella P, Moideen, Kadar, Banurekha, Vaithilingam V, Nair, Dina, Sridhar, Rathinam, Nutman, Thomas B, Babu, Subash
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578527/
https://ncbi.nlm.nih.gov/pubmed/26417443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.68
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