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Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain

BACKGROUND: West Nile virus (WNV) is a neurotropic flavivirus that has emerged globally as a significant cause of viral encephalitis in humans. Herein, we investigated the immunological responses induced by two phylogenetically related WNV strains of lineage 1, WNV NY99, and WNV Eg101. METHODS: Eigh...

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Publié dans:J Neuroinflammation
Auteurs principaux: Kumar, Mukesh, Roe, Kelsey, O’Connell, Maile, Nerurkar, Vivek R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578235/
https://ncbi.nlm.nih.gov/pubmed/26392176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0400-y
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