Staphylococcus aureus targets the Duffy antigen receptor for chemokines (DARC) to lyse erythrocytes

In order for Staphylococcus aureus to thrive inside the mammalian host, the bacterium has to overcome iron scarcity. S. aureus is thought to produce toxins that lyse erythrocytes, releasing hemoglobin, the most abundant iron source in mammals. Here we identify the Duffy antigen receptor for chemokin...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Spaan, András N., Reyes-Robles, Tamara, Badiou, Cédric, Cochet, Sylvie, Boguslawski, Kristina M., Yoong, Pauline, Day, Christopher J., de Haas, Carla J.C., van Kessel, Kok P.M., Vandenesch, François, Jennings, Michael P., Le Van Kim, Caroline, Colin, Yves, van Strijp, Jos A.G., Henry, Thomas, Torres, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578157/
https://ncbi.nlm.nih.gov/pubmed/26320997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.08.001
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