Stromal infiltration of CD8 T cells is associated with improved clinical outcome in HPV-positive oropharyngeal squamous carcinoma

BACKGROUND: Patients with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) have a better prognosis than those with HPV-negative tumours. There is interest in de-escalating their treatment but strategies are needed for risk stratification to identify subsets with a po...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Oguejiofor, K, Hall, J, Slater, C, Betts, G, Hall, G, Slevin, N, Dovedi, S, Stern, P L, West, C M L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578081/
https://ncbi.nlm.nih.gov/pubmed/26313665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.277
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