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Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells.

A DNA transfection protocol has been developed that makes use of the cyclic cationic amphipathic peptide gramicidin S and dioleoyl phosphatidylethanolamine. The DNA complex is formed by mixing gramicidin S with DNA at a 1:1 charge ratio and then adding phosphatidylethanolamine at a lipid/peptide mol...

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Autors principals: Legendre, J Y, Szoka, F C
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC45776/
https://ncbi.nlm.nih.gov/pubmed/7679217
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