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Cardiac Resynchronization Therapy Restores Sympathovagal Balance in the Failing Heart by Differential Remodeling of Cholinergic Signaling

RATIONALE: Cardiac resynchronization therapy (CRT) is the only heart failure (HF) therapy documented to improve left ventricular (LV) function and reduce mortality. The underlying mechanisms are incompletely understood. While β-adrenergic signaling has been studied extensively, the effect of CRT on...

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Publicado en:Circ Res
Autores principales: DeMazumder, Deeptankar, Kass, David A., O’Rourke, Brian, Tomaselli, Gordon F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577523/
https://ncbi.nlm.nih.gov/pubmed/25733594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.305268
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