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Evolving models of the immunopathogenesis of T-cell mediated drug allergy: the role of host, pathogens, and drug response
Immune-mediated adverse drug reactions (IM-ADRs) are an underrecognized source of preventable morbidity, mortality, and cost. Increasingly, genetic variation in the HLA loci is associated with risk of severe reactions, highlighting the importance of T-cell immune responses in the mechanisms of both...
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577472/ https://ncbi.nlm.nih.gov/pubmed/26254049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.05.050 |
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