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Effects of Microbubble Size on Ultrasound-Induced Transdermal Delivery of High-Molecular-Weight Drugs

The transdermal delivery of a wide range of high-molecular-weight drugs is limited by the stratum corneum layer of the epidermis representing a significant barrier to penetration across the skin. This study first determined the different effects of different-size ultrasound (US) contrast agents and...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Liao, Ai-Ho, Ho, Hsin-Chiao, Lin, Yi-Chun, Chen, Hang-Kang, Wang, Chih-Hung
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577131/
https://ncbi.nlm.nih.gov/pubmed/26390051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138500
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