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Selective nuclear export inhibitor KPT-330 enhances the antitumor activity of gemcitabine in human pancreatic cancer

Pancreatic cancer is an aggressive and deadly malignancy responsible for the death of over 37,000 Americans each year. Gemcitabine-based therapy is the standard treatment for pancreatic cancer but has limited efficacy due to chemoresistance. In this study, we evaluated the in vitro and in vivo effec...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Kazim, Sabiha, Malafa, Mokenge P., Coppola, Domenico, Husain, Kazim, Zibadi, Sherma, Kashyap, Trinayan, Crochiere, Marsha, Landesman, Yosef, Rashal, Tami, Sullivan, Daniel M., Mahipal, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577050/
https://ncbi.nlm.nih.gov/pubmed/25934708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0104
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