Validation of (64)Cu-ATSM damaging DNA via high-LET Auger electron emission

Radioactive copper (II) (diacetyl-bis N4-methylthiosemicarbazone) (Cu-ATSM) isotopes were originally developed for the imaging of hypoxia in tumors. Because the decay of a (64)Cu atom is emitting not only positrons but also Auger electrons, this radionuclide has great potential as a theranostic agen...

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Bibliografske podrobnosti
izdano v:J Radiat Res
Main Authors: McMillan, Dayton D., Maeda, Junko, Bell, Justin J., Genet, Matthew D., Phoonswadi, Garrett, Mann, Kelly A., Kraft, Susan L., Kitamura, Hisashi, Fujimori, Akira, Yoshii, Yukie, Furukawa, Takako, Fujibayashi, Yasuhisa, Kato, Takamitsu A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577009/
https://ncbi.nlm.nih.gov/pubmed/26251463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv042
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