Validation of (64)Cu-ATSM damaging DNA via high-LET Auger electron emission

Radioactive copper (II) (diacetyl-bis N4-methylthiosemicarbazone) (Cu-ATSM) isotopes were originally developed for the imaging of hypoxia in tumors. Because the decay of a (64)Cu atom is emitting not only positrons but also Auger electrons, this radionuclide has great potential as a theranostic agen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Radiat Res
Prif Awduron: McMillan, Dayton D., Maeda, Junko, Bell, Justin J., Genet, Matthew D., Phoonswadi, Garrett, Mann, Kelly A., Kraft, Susan L., Kitamura, Hisashi, Fujimori, Akira, Yoshii, Yukie, Furukawa, Takako, Fujibayashi, Yasuhisa, Kato, Takamitsu A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577009/
https://ncbi.nlm.nih.gov/pubmed/26251463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv042
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