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Fitness Trade-Offs Determine the Role of the Molecular Chaperonin GroEL in Buffering Mutations
Molecular chaperones fold many proteins and their mutated versions in a cell and can sometimes buffer the phenotypic effect of mutations that affect protein folding. Unanswered questions about this buffering include the nature of its mechanism, its influence on the genetic variation of a population,...
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| Veröffentlicht in: | Mol Biol Evol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576708/ https://ncbi.nlm.nih.gov/pubmed/26116858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv144 |
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