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Yeast expression and DNA immunization of hepatitis B virus S gene with second-loop deletion of α determinant region

AIM: Immune escape mutations of HBV often occur in the dominant epitope, the second-loop of the a determinant of hepatitis B surface antigen (HBsAg). To let the hosts respond to the subdominant epitopes in HBsAg may be an effective way to decrease the prevalence of immune escape mutants. For this re...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Hu, Hui, Peng, Xiao-Mou, Huang, Yang-Su, Gu, Lin, Xie, Qi-Feng, Gao, Zhi-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576258/
https://ncbi.nlm.nih.gov/pubmed/15378779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i20.2989
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