Construction of exogenous multiple epitopes of helper T lymphocytes and DNA immunization of its chimeric plasmid with HBV pre-S2/S gene

AIM: To design and construct an exogenous multiple epitope of helper T lymphocytes (HTL), and to evaluate its effect on anti-HBs response through DNA immunization. METHODS: Artificial HTL epitope, PADRE and four other HTL epitopes from different proteins were linked together using splicing by overla...

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Publicat a:World J Gastroenterol
Autors principals: Gao, Wen-Jun, Peng, Xiao-Mou, Xie, Dong-Ying, Xie, Qi-Feng, Gao, Zhi-Liang, Yao, Ji-Lu
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2004
Matèries:
Viral Hepatitis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576256/
https://ncbi.nlm.nih.gov/pubmed/15378777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i20.2979
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