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Effects of phosphorothioate anti-sense oligodeoxynucleotides on colorectal cancer cell growth and telomerase activity

AIM: To investigate the inhibitory effect of phosphorothioate anti-sense oligodeoxynucleotides (PASODN) on colorectal cancer LS-174T cells in vitro and the mechanism of inhibition of telomerase activity in these cells. METHODS: PASODN were used to infect LS-174T cells and block human telomerase RNA...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Wang, Xi-Shan, Wang, Kuan, Li, Xue, Fu, Song-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576226/
https://ncbi.nlm.nih.gov/pubmed/15526364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i23.3455
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