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Characterization of HIV-1 Resistance to Tenofovir Alafenamide In Vitro
Tenofovir alafenamide (TAF) is an investigational prodrug of the HIV-1 nucleotide reverse transcriptase (RT) inhibitor (NtRTI) tenofovir (TFV), with improved potency and drug delivery properties over the current prodrug, tenofovir disoproxil fumarate (TDF). TAF is currently in phase 3 clinical studi...
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Veröffentlicht in: | Antimicrob Agents Chemother |
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Hauptverfasser: | , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Microbiology
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576099/ https://ncbi.nlm.nih.gov/pubmed/26149983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01151-15 |
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