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Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation

Pharmacokinetic (PK) data describing a prolonged time course of antiretrovirals in plasma and peripheral blood mononuclear cells (PBMCs) are important for understanding and managing late or missed doses and to assess the appropriateness of compounds for preexposure prophylaxis (PrEP). This study aim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Dickinson, Laura, Yapa, H. Manisha, Jackson, Akil, Moyle, Graeme, Else, Laura, Amara, Alieu, Khoo, Saye, Back, David, Karolia, Zeenat, Higgs, Chris, Boffito, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576083/
https://ncbi.nlm.nih.gov/pubmed/26195515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01441-15
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