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Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical Practice

Based on a previously derived population pharmacokinetic model, a novel neonatal amikacin dosing regimen was developed. The aim of the current study was to prospectively evaluate this dosing regimen. First, early (before and after second dose) therapeutic drug monitoring (TDM) observations were eval...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Smits, A., De Cock, R. F. W., Allegaert, K., Vanhaesebrouck, S., Danhof, M., Knibbe, C. A. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576045/
https://ncbi.nlm.nih.gov/pubmed/26248375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01157-15
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