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Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical Practice

Based on a previously derived population pharmacokinetic model, a novel neonatal amikacin dosing regimen was developed. The aim of the current study was to prospectively evaluate this dosing regimen. First, early (before and after second dose) therapeutic drug monitoring (TDM) observations were eval...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Smits, A., De Cock, R. F. W., Allegaert, K., Vanhaesebrouck, S., Danhof, M., Knibbe, C. A. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576045/
https://ncbi.nlm.nih.gov/pubmed/26248375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01157-15
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