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Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness

There is considerable concern that malaria parasites are starting to evolve resistance to the current generation of antimalarial drugs, the artemisinin-based combination therapies (ACTs). We use pharmacological modeling to investigate changes in ACT effectiveness likely to occur if current regimens...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kay, Katherine, Hodel, Eva Maria, Hastings, Ian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576027/
https://ncbi.nlm.nih.gov/pubmed/26239993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00482-15
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