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Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth

Recent studies have shown that the gip2 and gep oncogenes defined by the α-subunits of Gi2 and G12 family of G proteins, namely Gαi2 and Gα12/13, stimulate oncogenic signaling pathways in cancer cells including those derived from ovarian cancer. However, the critical α-subunit involved in ovarian ca...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Cancer
Hauptverfasser: Ha, Ji Hee, Gomathinayagam, Rohini, Yan, Mingda, Jayaraman, Muralidharan, Ramesh, Rajagopal, Dhanasekaran, Danny N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575922/
https://ncbi.nlm.nih.gov/pubmed/26413218
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