LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

BACKGROUND: Within the last few years, it has become evident that LPS-preconditioned mesenchymal stromal cells (LPS pre-MSCs) show enhanced paracrine effects, including increased trophic support and improved regenerative and repair properties. MSCs may release large amounts of exosomes for cell-to-c...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ti, Dongdong, Hao, Haojie, Tong, Chuan, Liu, Jiejie, Dong, Liang, Zheng, Jingxi, Zhao, Yali, Liu, Huiling, Fu, Xiaobing, Han, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575470/
https://ncbi.nlm.nih.gov/pubmed/26386558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0642-6
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