Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

BACKGROUND: Sphingolipids constitute bioactive molecules with functional implications in liver homeostasis. Particularly, ablation of very long chain ceramides in a knockout mouse model has been shown to cause a severe hepatopathy. METHODS: We aimed to evaluate the serum sphingolipid profile of 244...

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Udgivet i:PLoS One
Main Authors: Grammatikos, Georgios, Ferreiròs, Nerea, Waidmann, Oliver, Bon, Dimitra, Schroeter, Sirkka, Koch, Alexander, Herrmann, Eva, Zeuzem, Stefan, Kronenberger, Bernd, Pfeilschifter, Josef
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575185/
https://ncbi.nlm.nih.gov/pubmed/26382760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138130
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