Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker

BACKGROUND: Establishment of a biological pacemaker is expected to solve the persisting problems of a mechanical pacemaker including the problems of battery life and electromagnetic interference. Enhancement of the funny current (I (f)) flowing through hyperpolarization-activated cyclic nucleotide-g...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saito, Yukihiro, Nakamura, Kazufumi, Yoshida, Masashi, Sugiyama, Hiroki, Ohe, Tohru, Kurokawa, Junko, Furukawa, Tetsushi, Takano, Makoto, Nagase, Satoshi, Morita, Hiroshi, Kusano, Kengo F., Ito, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575154/
https://ncbi.nlm.nih.gov/pubmed/26384234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138193
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