Inferring Protective CD8(+) T-Cell Epitopes for NS5 Protein of Four Serotypes of Dengue Virus Chinese Isolates Based on HLA-A, -B and -C Allelic Distribution: Implications for Epitope-Based Universal Vaccine Design

Dengue is one of the most globally serious vector-borne infectious diseases in tropical and subtropical areas for which there are currently no effective vaccines. The most highly conserved flavivirus protein, NS5, is an indispensable target of CD8(+) T-cells, making it an ideal vaccine design target...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Shi, Jiandong, Sun, Jing, Wu, Meini, Hu, Ningzhu, Li, Jianfan, Li, Yanhan, Wang, Haixuan, Hu, Yunzhang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575106/
https://ncbi.nlm.nih.gov/pubmed/26381649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138729
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