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Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in the brain, leading to a Parkinson related disease, called manganism. Versatile mechanisms of Mn-induced brain injury are discussed, with inactivation of mitochondrial defense against oxidative stress...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Neth, Katharina, Lucio, Marianna, Walker, Alesia, Zorn, Julia, Schmitt-Kopplin, Philippe, Michalke, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575095/
https://ncbi.nlm.nih.gov/pubmed/26383269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138270
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