Protein binding characteristics and pharmacokinetics of ceftriaxone in intensive care unit patients

AIMS: The aim of the present study was to assess the pharmacokinetics of total and unbound ceftriaxone in intensive care unit (ICU) patients and its protein binding characteristics. METHODS: Twenty patients (m/f 15/5, age 25–86 years, body weight 60–121 kg, APACHE II 7–40, estimated glomerular filtr...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Schleibinger, Michael, Steinbach, Cathérine L, Töpper, Christoph, Kratzer, Alexander, Liebchen, Uwe, Kees, Frieder, Salzberger, Bernd, Kees, Martin G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574837/
https://ncbi.nlm.nih.gov/pubmed/25808018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12636
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