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Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action

ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. These two classes of drug act by curtailing the actions of angiotensin II-linked inflammatory pathways that are up-regulated during gamma radiation in...

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Publié dans:PLoS One
Auteurs principaux: Wang, Hong, Sethi, Gautam, Loke, Weng-Keong, Sim, Meng-Kwoon
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574738/
https://ncbi.nlm.nih.gov/pubmed/26378927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138009
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