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Tumor Necrosis Factor - Alpha Is Essential for Angiotensin II-Induced Ventricular Remodeling: Role for Oxidative Stress

The functional crosstalk between angiotensin II (Ang II) and tumor necrosis factor (TNF)-α has been shown to cause adverse left ventricular remodeling and hypertrophy in hypertension. Previous studies from our lab showed that mice lacking TNF-α (TNF-α(-/-)) have attenuated hypertensive response to A...

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Bibliographic Details
Published in:PLoS One
Main Authors: Sriramula, Srinivas, Francis, Joseph
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574701/
https://ncbi.nlm.nih.gov/pubmed/26378790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138372
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