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Loss of Methylation at H19 DMD Is Associated with Biallelic Expression and Reduced Development in Cattle Derived by Somatic Cell Nuclear Transfer

Although cloning of mammals has been achieved successfully, the percentage of live offspring is very low because of reduced fetal size and fewer implantation sites. Recent studies have attributed such pathological conditions to abnormal reprogramming of the donor cell used for cloning. The inability...

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Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Suzuki, J., Therrien, J., Filion, F., Lefebvre, R., Goff, A.K., Perecin, F., Meirelles, F.V., Smith, L.C.
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574635/
https://ncbi.nlm.nih.gov/pubmed/21248292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.110.087833
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