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Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma

Loss of the chromosomal region 8p21 negatively effects survival in patients with multiple myeloma (MM) that undergo autologous stem cell transplantation (ASCT). In this study, we aimed to identify the immunological and molecular consequences of del(8)(p21) with regards to treatment response and bort...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Duru, Adil Doganay, Sutlu, Tolga, Wallblom, Ann, Uttervall, Katarina, Lund, Johan, Stellan, Birgitta, Gahrton, Gösta, Nahi, Hareth, Alici, Evren
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574561/
https://ncbi.nlm.nih.gov/pubmed/26378933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138248
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