Up-regulation of A20/ABIN1 contributes to inefficient M1 macrophage polarization during Hepatitis C virus infection

BACKGROUND: Anti-hepatitis C virus (HCV) responses are often accompanied by an increase in alanine aminotransferase levels in HCV-infected patients, indicating that inflammatory responses are compromised by the virus. Additionally, inflammation is associated with M1-polarizated macrophages, which se...

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Publicado en:Virol J
Autores principales: Fan, Chao, Zhang, Ying, Zhou, Yun, Li, Bingjie, He, Yu, Guo, Yonghong, Jia, Zhansheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574525/
https://ncbi.nlm.nih.gov/pubmed/26382585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0379-0
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