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Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials

BACKGROUND: Trials in Alzheimer’s disease are increasingly focusing on prevention in asymptomatic individuals. This poses a challenge in examining treatment effects since currently available approaches are often unable to detect cognitive and functional changes among asymptomatic individuals. Result...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dodge, Hiroko H., Zhu, Jian, Mattek, Nora C., Austin, Daniel, Kornfeld, Judith, Kaye, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574479/
https://ncbi.nlm.nih.gov/pubmed/26379170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138095
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