Major depressive disorder as a nonlinear dynamic system: bimodality in the frequency distribution of depressive symptoms over time

BACKGROUND: A defining characteristic of Major Depressive Disorder (MDD) is its episodic course, which might indicate that MDD is a nonlinear dynamic phenomenon with two discrete states. We investigated this hypothesis using the symptom time series of individual patients. METHODS: In 178 primary car...

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Veröffentlicht in:BMC Psychiatry
Hauptverfasser: Hosenfeld, Bettina, Bos, Elisabeth H., Wardenaar, Klaas J., Conradi, Henk Jan, van der Maas, Han L. J., Visser, Ingmar, de Jonge, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574448/
https://ncbi.nlm.nih.gov/pubmed/26385384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-015-0596-5
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