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Dopamine agonist inhibits vascular endothelial growth factor protein production and secretion in granulosa cells

BACKGROUND: Dopamine receptor 2 agonists (D2-ags) inhibit vascular endothelial growth factor (VEGF) secretion in luteinized granulosa cells (LGCs) both in vitro and in vivo. However, the mechanism of D2 regulation of the VEGF/VEGF Receptor 2 (VEGFR-2) pathway remains to be elucidated. We sought to d...

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Pubblicato in:Reprod Biol Endocrinol
Autori principali: Ferrero, Hortensia, García-Pascual, Carmen M., Pellicer, Nuria, Simón, Carlos, Pellicer, Antonio, Gómez, Raúl
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574352/
https://ncbi.nlm.nih.gov/pubmed/26377185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-015-0102-4
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