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A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division

Mitochondrial division, essential for survival in mammals, is enhanced by an inter-organellar process involving ER tubules encircling and constricting mitochondria. The force for constriction is thought to involve actin polymerization by the ER-anchored isoform of the formin protein inverted formin...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Manor, Uri, Bartholomew, Sadie, Golani, Gonen, Christenson, Eric, Kozlov, Michael, Higgs, Henry, Spudich, James, Lippincott-Schwartz, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574297/
https://ncbi.nlm.nih.gov/pubmed/26305500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08828
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