Cyclosporine A Treatment Inhibits Abcc6-Dependent Cardiac Necrosis and Calcification following Coxsackievirus B3 Infection in Mice

Coxsackievirus type B3 (CVB3) is a cardiotropic enterovirus. Infection causes cardiomyocyte necrosis and myocardial inflammation. The damaged tissue that results is replaced with fibrotic or calcified tissue, which can lead to permanently altered cardiac function. The extent of pathogenesis among in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Marton, Jennifer, Albert, Danica, Wiltshire, Sean A., Park, Robin, Bergen, Arthur, Qureshi, Salman, Malo, Danielle, Burelle, Yan, Vidal, Silvia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574283/
https://ncbi.nlm.nih.gov/pubmed/26375467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138222
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