Low-Frequency IL23R Coding Variant Associated with Crohn’s Disease Susceptibility in Japanese Subjects Identified by Personal Genomics Analysis

BACKGROUND: The common disease-common variant hypothesis is insufficient to explain the complexities of Crohn’s disease (CD) genetics; therefore, rare variants are expected to be important in the disease. We explored rare variants associated with susceptibility to CD in Japanese individuals by perso...

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Pubblicato in:PLoS One
Autori principali: Onodera, Kei, Arimura, Yoshiaki, Isshiki, Hiroyuki, Kawakami, Kentaro, Nagaishi, Kanna, Yamashita, Kentaro, Yamamoto, Eiichiro, Niinuma, Takeshi, Naishiro, Yasuyoshi, Suzuki, Hiromu, Imai, Kohzoh, Shinomura, Yasuhisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574159/
https://ncbi.nlm.nih.gov/pubmed/26375822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137801
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